Clinically proven to support sleep quality and improve mood.

NIGHT uses affron® which is standardised to a minimum of 3.5% active components, known as lepticrosalasides, and is the most clinically backed saffron ingredient worldwide.

Studies show affron® consumption increases melatonin levels. This marries up with studies on Montmorency tart cherry whose rich procyanidin-B2 levels increase tryptophan availability as tryptophan is the precursor to melatonin synthesis.

In a double blind placebo trial, affron® intake for 28 days :

• Significant reduction of 25% of the Insomnia Severity Index Score
• Significant increase of 20% of the Restorative Sleep Questionnaire (RSQ), related to feeling more energised after awakening
• Significant improvement in alertness upon awakening

25% Reduction in Sleeplessness

Insomnia Severity Index Score

Affron® improves mental outlook

In a randomised, double-blind placebo-controlled study Affron® intake for 4 weeks, showed signs of improved mood and alleviated occasional stress or tension related anxieties and associated fatigue.

Decreases blood markers of inflammation and cellular stress.

Tart Cherry is a powerful natural ingredient, packed with anthocyanins and procyanidins – compounds renowned for their ability to combat inflammation, reduce oxidative stress, and support recovery. Unlike sweet cherries, Tart Cherry delivers 93% cyanidin-based anthocyanins, which are particularly effective for improving both physical recovery and sleep quality.

A placebo-controlled balanced crossover study demonstrated the following benefits for improving sleep and recovery. (i)

Enhances Sleep Duration and Quality

Tart Cherry increases sleep time and efficiency by improving tryptophan availability in the bloodstream, supporting serotonin and melatonin production.

Increases sleep duration by 84 minutes.

Improved sleep efficiency post-treatment.

Reduces Inflammation/Recovery Support

Tart Cherry reduces markers of inflammation and oxidative stress, helping you recover faster and perform better.

Decreased Prostaglandin E2 levels, reflecting reduced inflammation.

The amino acid for rest and revitalisation.

Glycine is an amino acid that works as a neurotransmitter in the brain influencing how we sleep. (ix) 3g Glycine ingestion before bed shortens sleep latency, increases sleep efficiency, and reduces daytime sleepiness in healthy adults, as well as helping people cope with sleep loss.(xi) These sleep-promoting effects appear to be mediated through activity on our body clocks causing a decrease in the core body temperature.

Unlike other common sleep aids, no negative or hangover effects are observed with descriptions of “liveliness and peppiness”, and “clear-headedness” being noted by individuals on how they felt the next day.(xii) Beyond sleep, Glycine must be considered an essential amino acid for active individuals because the capacity of its synthesis is much lower than its actual need. Increasing glycine in the diet improves cartilage regeneration by means of enhancing collagen synthesis improving the health of bones, tendons, ligaments and skin.(xiii)

Sleep Quality and Duration

1. Sleep efficiency increased from 72.5% (placebo) to 81.8% (glycine).
2. Sleep latency decreased from 14.3 minutes (placebo) to 10.6 minutes (glycine)

Effects of Glycine on Sleep (Inagawa et al., 2006):

Daytime Performance (Bannai et al., 2012):

1. Fatigue scores decreased from 5.0 (placebo) to 3.5 (glycine).
2. Reaction times improved from 355ms (placebo) to 315ms (glycine).

Fatigue Score (VAS)